AIF Insights No. 20 (2025) | Buddha: Proto-Neuroscientist and Forerunner of AI Thought

AIF Insights No. 20 (2025) | Buddha: Proto-Neuroscientist and Forerunner of AI Thought

Release: 2025-05-18
By: CHHEM Kieth Rethy, MD, PhD (Edu), and PhD (His)

This essay proposes that Siddhartha Gautama, the historical Buddha, can be seen as a proto-neuroscientist and early theorist of artificial intelligence. Through systematic introspection, ethical discipline, and meditative practices, the Buddha developed a sophisticated cognitive framework that parallels modern discoveries in neuroscience, psychology, and AI. His teachings on dependent origination resemble feedback and predictive coding models, while practices like mindfulness and compassion align with contemporary understandings of neuroplasticity and affective regulation. The Buddha’s logic, especially the tetralemma (catuṣkoṭi), anticipates non-binary reasoning useful in complex AI systems. Moreover, Buddhist epistemology and the integration of ethics into cognition offer a compelling model for AI design—one where ethical awareness is foundational rather than peripheral. Ultimately, the essay argues for the relevance of Buddhist insights in developing humane, adaptive, and ethically grounded AI, with the Buddha’s vision of compassionate wisdom serving as a vital guide for the future of intelligent systems.